Burkholderia cenocepacia J2315, BCAL0323 (tatA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL0323
NCBI Locus TagQU43_RS38145
Name
tatA
Replicon chromosome 1
Genomic location 352214 - 352444 (+ strand)
CommentRequired for growth in the presence of 20__M CuSO4 (PMID:32090500)

Cross-References

RefSeq WP_006477115.1
GI 206558729
Entrez 6930874
GI 206558729
INSDC CAR50633.1
NCBI Locus Tag QU43_RS38145
NCBI Old Locus Tag BCAL0323
RefSeq WP_006477115.1,GeneID
UniParc UPI000052EADD
UniProtKB Acc B4E646
UniProtKB ID TATA_BURCJ
UniRef100 UniRef100_Q1BS36
UniRef50 UniRef50_Q2SUB3
UniRef90 UniRef90_Q2SUB3

Product

Feature Type CDS
Coding Frame 1
Product Name
twin arginine translocase protein A
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 2.22
Kyte-Doolittle Hydrophobicity Value -0.168
Molecular Weight (kDa) 8123.3
Isoelectric Point (pI) 10.03

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 200 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000344 (656 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL0323
Search term: tatA

Human Homologs

References

Copper resistance genes of Burkholderia cenocepacia H111 identified by transposon sequencing.
Higgins S, Gualdi S, Pinto-Carbó M, Eberl L
Environ Microbiol Rep 2020 Apr;12(2):241-249
PubMed ID: 32090500