Burkholderia glumae BGR1, bglu_2g06360 (toxH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia glumae BGR1
GCF_000022645.2|latest
Locus Tag
bglu_2g06360
NCBI Locus TagBGLU_RS21035
Name
toxH
Replicon chromosome 2
Genomic location 762722 - 765814 (- strand)
CommentMember of the toxoflavin transporter gene cluster

Cross-References

RefSeq WP_012733467.1
GI
Entrez 7904510
NCBI Locus Tag BGLU_RS21035
NCBI Old Locus Tag bglu_2g06360
RefSeq WP_012733467.1,GeneID

Product

Feature Type CDS
Coding Frame 1
Product Name
ToxH
Product Name Confidence: Class 2
Synonyms putative RND efflux transporter
Evidence for Translation
Charge (pH 7) 4.40
Kyte-Doolittle Hydrophobicity Value 0.443
Molecular Weight (kDa) 110121.1
Isoelectric Point (pI) 8.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 487 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG035429 (43 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: bglu_2g06360
Search term: toxH
Search term: ToxH

Human Homologs

References

Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae.
Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I
Mol Microbiol 2004 Nov;54(4):921-34
PubMed ID: 15522077
Biochemical Characterization and Structural Basis of Reactivity and Regioselectivity Differences between Burkholderia thailandensis and Burkholderia glumae 1,6-Didesmethyltoxoflavin N-Methyltransferase.
Fenwick MK, Almabruk KH, Ealick SE, Begley TP, Philmus B
Biochemistry 2017 Aug 1;56(30):3934-3944
PubMed ID: 28665591