Burkholderia cenocepacia J2315, BCAS0222 (afcA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia cenocepacia J2315
GCF_000009485.1|latest |
| Locus Tag |
BCAS0222
|
| NCBI Locus Tag | QU43_RS69790 |
| Name |
afcA
|
| Replicon | chromosome 3 |
| Genomic location | 238980 - 240743 (- strand) |
Cross-References
| RefSeq | YP_002153612.1 |
| GI | 197295071 |
| Entrez | 6804595 |
| GI | 197295071 |
| NCBI Locus Tag | QU43_RS69790 |
| NCBI Old Locus Tag | BCAS0222 |
| RefSeq | YP_002153612.1 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
putative AMP-dependent synthetase
|
| Synonyms |
putative amino acid activating protein |
| Evidence for Translation | |
| Charge (pH 7) | -6.23 |
| Kyte-Doolittle Hydrophobicity Value | 0.059 |
| Molecular Weight (kDa) | 62442.4 |
| Isoelectric Point (pI) | 6.36 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 575 genera
|
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG001460 (2297 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: BCAS0222
Search term: afcA
Search term: putative AMP-dependent synthetase
|
Human Homologs
|
Ensembl
97, assembly
GRCh38.p12
|
acyl-CoA synthetase long chain family member 5 [Source:HGNC Symbol;Acc:HGNC:16526]
E-value:
4.9e-07
Percent Identity:
44.3
|
|
Ensembl
97, assembly
GRCh38.p12
|
acyl-CoA synthetase long chain family member 5 [Source:HGNC Symbol;Acc:HGNC:16526]
E-value:
4.9e-07
Percent Identity:
44.3
|
|
Ensembl
97, assembly
GRCh38.p12
|
acyl-CoA synthetase long chain family member 5 [Source:HGNC Symbol;Acc:HGNC:16526]
E-value:
4.9e-07
Percent Identity:
44.3
|
|
Ensembl
97, assembly
GRCh38.p12
|
acyl-CoA synthetase long chain family member 5 [Source:HGNC Symbol;Acc:HGNC:16526]
E-value:
4.9e-07
Percent Identity:
44.3
|
|
Ensembl
97, assembly
GRCh38.p12
|
acyl-CoA synthetase long chain family member 5 [Source:HGNC Symbol;Acc:HGNC:16526]
E-value:
4.9e-07
Percent Identity:
44.3
|
References
|
Characterization of genes involved in biosynthesis of a novel antibiotic from Burkholderia cepacia BC11 and their role in biological control of Rhizoctonia solani.
Kang Y, Carlson R, Tharpe W, Schell MA
Appl Environ Microbiol 1998 Oct;64(10):3939-47
PubMed ID: 9758823
|