Burkholderia cenocepacia J2315, BCAS0201 (afcF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAS0201
NCBI Locus TagQU43_RS69685
Name
afcF
Replicon chromosome 3
Genomic location 217322 - 218740 (- strand)

Cross-References

RefSeq WP_012493693.1
GI 197295051
Entrez 6804105
GI 197295051
INSDC CAR57133.1
NCBI Locus Tag QU43_RS69685
NCBI Old Locus Tag BCAS0201
RefSeq WP_012493693.1,GeneID
UniParc UPI00017BB22A
UniProtKB Acc B4EPW7
UniProtKB ID B4EPW7_BURCJ
UniRef100 UniRef100_A0A0D1C9R5
UniRef50 UniRef50_Q0B2F0
UniRef90 UniRef90_G7HPT0

Product

Feature Type CDS
Coding Frame 1
Product Name
AfcF
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -0.20
Kyte-Doolittle Hydrophobicity Value 0.334
Molecular Weight (kDa) 48726.1
Isoelectric Point (pI) 6.97

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 520 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG005255 (86 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAS0201
Search term: afcF
Search term: AfcF

Human Homologs

References

Role of Burkholderia cenocepacia afcE and afcF genes in determining lipid-metabolism-associated phenotypes.
Subramoni S, Agnoli K, Eberl L, Lewenza S, Sokol PA
Microbiology 2013 Mar;159(Pt 3):603-614
PubMed ID: 23306671
Burkholderia cenocepacia ShvR-regulated genes that influence colony morphology, biofilm formation, and virulence.
Subramoni S, Nguyen DT, Sokol PA
Infect Immun 2011 Aug;79(8):2984-97
PubMed ID: 21690240