Burkholderia cenocepacia J2315, BCAM2226

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM2226
NCBI Locus TagQU43_RS65500
Name
Replicon chromosome 2
Genomic location 2488447 - 2490168 (- strand)

Cross-References

RefSeq WP_006483270.1
GI 206564063
Entrez 6929812
GI 206564063
INSDC CAR56084.1
NCBI Locus Tag QU43_RS65500
NCBI Old Locus Tag BCAM2226
RefSeq WP_006483270.1,GeneID
UniParc UPI00017B9FE2
UniProtKB Acc B4EGF8
UniProtKB ID B4EGF8_BURCJ
UniRef100 UniRef100_B4EGF8
UniRef50 UniRef50_Q399S2
UniRef90 UniRef90_G7HSN4

Product

Feature Type CDS
Coding Frame 1
Product Name
ABC transporter ATP-binding membrane protein
Synonyms
Evidence for Translation
Charge (pH 7) 9.41
Kyte-Doolittle Hydrophobicity Value 0.346
Molecular Weight (kDa) 60388.1
Isoelectric Point (pI) 8.95

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006692 (374 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM2226

Human Homologs

Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 6 (Langereis blood group) [Source:HGNC Symbol;Acc:HGNC:47]
E-value: 1.4e-38
Percent Identity: 37.8
Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 6 (Langereis blood group) [Source:HGNC Symbol;Acc:HGNC:47]
E-value: 1.4e-38
Percent Identity: 37.8

References

Dihydroaeruginoic acid synthetase and pyochelin synthetase, products of the pchEF genes, are induced by extracellular pyochelin in Pseudomonas aeruginosa.
Reimmann C, Serino L, Beyeler M, Haas D
Microbiology 1998 Nov;144 ( Pt 11):3135-48
PubMed ID: 9846750
Erratum in: J Bacteriol. 2009 Apr;191(8):2907.
The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients.
J Bacteriol. 2009 Jan;191(1):261-77.
PubMed ID: 18931103