Burkholderia cenocepacia J2315, BCAM2225

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM2225
NCBI Locus TagQU43_RS65495
Name
Replicon chromosome 2
Genomic location 2486684 - 2488450 (- strand)

Cross-References

RefSeq YP_002234825.1
GI 206564062
Entrez 6929811
GI 206564062
INSDC CAR56083.1
NCBI Locus Tag QU43_RS65495
NCBI Old Locus Tag BCAM2225
RefSeq YP_002234825.1
UniParc UPI00017B9FE1
UniProtKB Acc B4EGF7
UniProtKB ID B4EGF7_BURCJ
UniRef100 UniRef100_B4EGF7
UniRef50 UniRef50_Q2RW50
UniRef90 UniRef90_Q399S1

Product

Feature Type CDS
Coding Frame 1
Product Name
ABC transporter ATP-binding membrane protein
Synonyms
Evidence for Translation
Charge (pH 7) 15.20
Kyte-Doolittle Hydrophobicity Value 0.259
Molecular Weight (kDa) 62236.4
Isoelectric Point (pI) 10.62

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006691 (377 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM2225

Human Homologs

Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 6 (Langereis blood group) [Source:HGNC Symbol;Acc:HGNC:47]
E-value: 1.6e-29
Percent Identity: 35.1
Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 6 (Langereis blood group) [Source:HGNC Symbol;Acc:HGNC:47]
E-value: 1.6e-29
Percent Identity: 35.1

References

Dihydroaeruginoic acid synthetase and pyochelin synthetase, products of the pchEF genes, are induced by extracellular pyochelin in Pseudomonas aeruginosa.
Reimmann C, Serino L, Beyeler M, Haas D
Microbiology 1998 Nov;144 ( Pt 11):3135-48
PubMed ID: 9846750
Erratum in: J Bacteriol. 2009 Apr;191(8):2907.
The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients.
J Bacteriol. 2009 Jan;191(1):261-77.
PubMed ID: 18931103