Burkholderia cenocepacia J2315, BCAM1494 (bceS1)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM1494
NCBI Locus Tag	QU43_RS61820
Name	bceS1
Replicon	chromosome 2
Genomic location	1658026 - 1660128 (- strand)

Cross-References

RefSeq	WP_012493327.1
GI	206563344
Entrez	6929141
GI	206563344
INSDC	CAR55349.1
NCBI Locus Tag	QU43_RS61820
NCBI Old Locus Tag	BCAM1494
RefSeq	WP_012493327.1,GeneID
UniParc	UPI00017B9EEF
UniProtKB Acc	B4EJI5
UniProtKB ID	B4EJI5_BURCJ
UniRef100	UniRef100_B4EJI5
UniRef50	UniRef50_A3NJV8
UniRef90	UniRef90_Q395U6

Product

Feature Type	CDS
Coding Frame	1
Product Name	two-component regulatory system sensor kinase BceS1 Product Name Confidence: Class 1
Synonyms	two-component regulatory system sensor kinase
Evidence for Translation
Charge (pH 7)	2.11
Kyte-Doolittle Hydrophobicity Value	-0.058
Molecular Weight (kDa)	74785.4
Isoelectric Point (pI)	7.48

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 482 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003440 (815 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM1494 Search term: bceS1 Search term: two-component regulatory system sensor kinase BceS1

Human Homologs

References

Characterization of a novel two-component system in Burkholderia cenocepacia. Merry CR, Perkins M, Mu L, Peterson BK, Knackstedt RW, Weingart CL Curr Microbiol 2015 Apr;70(4):556-61 PubMed ID: 25519693