Burkholderia cenocepacia J2315, BCAM1011 (bceU)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM1011
NCBI Locus TagQU43_RS59435
Name
bceU
Replicon chromosome 2
Genomic location 1124364 - 1125482 (- strand)
CommentMember of the bce-II gene cluster
CommentSince bceU is found in the genome sequences of all Bcc strains as well as in B. thailandensis, B. oklahomensis, and B. pseudomallei strains, the authors of PMID:19948863 considered it to belong as part of bce-II gene cluster.

Cross-References

RefSeq WP_012493217.1
GI 206562866
Entrez 6930487
GI 206562866
INSDC CAR54868.1
NCBI Locus Tag QU43_RS59435
NCBI Old Locus Tag BCAM1011
RefSeq WP_012493217.1,GeneID
UniParc UPI00017B9DE2
UniProtKB Acc B4EFL9
UniProtKB ID B4EFL9_BURCJ
UniRef100 UniRef100_A0A0D1DLV8
UniRef50 UniRef50_J7JIC9
UniRef90 UniRef90_B1K349

Product

Feature Type CDS
Coding Frame 1
Product Name
acyltransferase BceU
Product Name Confidence: Class 2
Synonyms putative acetyltransferase
Evidence for Translation
Charge (pH 7) 13.25
Kyte-Doolittle Hydrophobicity Value 0.775
Molecular Weight (kDa) 40142.1
Isoelectric Point (pI) 9.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 233 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003110 (627 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM1011
Search term: bceU

Human Homologs

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863