Burkholderia cenocepacia J2315, BCAM0863 (bceJ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM0863
NCBI Locus TagQU43_RS58695
Name
bceJ
Replicon chromosome 2
Genomic location 952967 - 954151 (+ strand)
CommentMember of the bce-I gene cluster

Cross-References

RefSeq WP_006482819.1
GI 206562719
Entrez 6930378
GI 206562719
INSDC CAR54721.1
NCBI Locus Tag QU43_RS58695
NCBI Old Locus Tag BCAM0863
RefSeq WP_006482819.1,GeneID
UniParc UPI00017B9A2C
UniProtKB Acc B4EMY2
UniProtKB ID B4EMY2_BURCJ
UniRef100 UniRef100_A0A095EAK8
UniRef50 UniRef50_Q393I7
UniRef90 UniRef90_Q393I7

Product

Feature Type CDS
Coding Frame 1
Product Name
BceJ
Product Name Confidence: Class 2
Synonyms putative glycosyltransferase
Evidence for Translation
Charge (pH 7) 9.58
Kyte-Doolittle Hydrophobicity Value -0.008
Molecular Weight (kDa) 43213.2
Isoelectric Point (pI) 9.55

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 588 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004855 (633 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0863
Search term: bceJ
Search term: BceJ

Human Homologs

References

Identification and physical organization of the gene cluster involved in the biosynthesis of Burkholderia cepacia complex exopolysaccharide.
Moreira LM, Videira PA, Sousa SA, Leitão JH, Cunha MV, Sá-Correia I
Biochem Biophys Res Commun 2003 Dec 12;312(2):323-33
PubMed ID: 14637140
Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863
Insights into the role of extracellular polysaccharides in Burkholderia adaptation to different environments.
Ferreira AS, Silva IN, Oliveira VH, Cunha R, Moreira LM
Front Cell Infect Microbiol 2011;1:16
PubMed ID: 22919582