Burkholderia cenocepacia J2315, BCAM0334 (virB11)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM0334
NCBI Locus TagQU43_RS56075
Name
virB11
Synonym: bcvirB11
Replicon chromosome 2
Genomic location 388346 - 389443 (+ strand)
CommentThis gene is part of the B. cenocepacia J2315 VirB-VirD-like type IV secretion system cluster.

Cross-References

RefSeq YP_002232963.1
GI 206562200
Entrez 6928123
GI 206562200
NCBI Locus Tag QU43_RS56075
NCBI Old Locus Tag BCAM0334
RefSeq YP_002232963.1
UniProtKB Acc B4EIS5
UniProtKB ID B4EIS5_BURCJ

Product

Feature Type CDS
Coding Frame 1
Product Name
putative type IV secretion system protein VirB11
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -2.77
Kyte-Doolittle Hydrophobicity Value -0.056
Molecular Weight (kDa) 40582.2
Isoelectric Point (pI) 6.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 422 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006330 (72 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0334
Search term: virB11

Human Homologs

References

Involvement of a plasmid-encoded type IV secretion system in the plant tissue watersoaking phenotype of Burkholderia cenocepacia.
Engledow AS, Medrano EG, Mahenthiralingam E, LiPuma JJ, Gonzalez CF
J Bacteriol 2004 Sep;186(18):6015-24
PubMed ID: 15342570
Two type IV secretion systems with different functions in Burkholderia cenocepacia K56-2.
Zhang R, LiPuma JJ, Gonzalez CF
Microbiology 2009 Dec;155(Pt 12):4005-4013
PubMed ID: 19744991
A type IV secretion system contributes to intracellular survival and replication of Burkholderia cenocepacia.
Sajjan SU, Carmody LA, Gonzalez CF, LiPuma JJ
Infect Immun 2008 Dec;76(12):5447-55
PubMed ID: 18824538