Burkholderia cenocepacia J2315, BCAM0239a (cciI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM0239a
NCBI Locus TagQU43_RS55620
Name
cciI
Replicon chromosome 2
Genomic location 296654 - 297277 (- strand)

Cross-References

RefSeq YP_002232872.1
GI 206562109
Entrez 6928036
GI 206562109
INSDC CAR54099.1
NCBI Locus Tag QU43_RS55620
NCBI Old Locus Tag BCAM0239a
RefSeq WP_012493039.1,GeneID
UniParc UPI00017B9A0B
UniProtKB Acc B4EI52
UniProtKB ID B4EI52_BURCJ
UniRef100 UniRef100_B4EI52
UniRef50 UniRef50_B4EI52
UniRef90 UniRef90_B4EI52

Product

Feature Type CDS
Coding Frame 1
Product Name
N-acylhomoserine lactone synthase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 2.21
Kyte-Doolittle Hydrophobicity Value 0.239
Molecular Weight (kDa) 22373.6
Isoelectric Point (pI) 7.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 45 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003720 (981 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0239a
Search term: cciI

Human Homologs

References

The Burkholderia cepacia epidemic strain marker is part of a novel genomic island encoding both virulence and metabolism-associated genes in Burkholderia cenocepacia.
Baldwin A, Sokol PA, Parkhill J, Mahenthiralingam E
Infect Immun 2004 Mar;72(3):1537-47
PubMed ID: 14977960
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
Infect Immun 2005 Aug;73(8):4982-92
PubMed ID: 16041013