Burkholderia cenocepacia J2315, BCAM0222

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM0222
NCBI Locus TagQU43_RS55530
Name
Replicon chromosome 2
Genomic location 269998 - 270690 (- strand)

Cross-References

RefSeq WP_006489567.1
GI 206562092
Entrez 6928017
GI 206562092
INSDC CAR54080.1
NCBI Locus Tag QU43_RS55530
NCBI Old Locus Tag BCAM0222
RefSeq WP_006489567.1,GeneID
UniParc UPI00017B9DF7
UniProtKB Acc B4EHQ4
UniProtKB ID B4EHQ4_BURCJ
UniRef100 UniRef100_B4EHQ4
UniRef50 UniRef50_A0A095DI18
UniRef90 UniRef90_B4EHQ4

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component regulatory system response regulator protein
Synonyms
Evidence for Translation
Charge (pH 7) 1.34
Kyte-Doolittle Hydrophobicity Value 0.135
Molecular Weight (kDa) 24883.6
Isoelectric Point (pI) 7.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 462 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003783 (1065 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0222

Human Homologs

References

A BCAM0223 mutant of Burkholderia cenocepacia is deficient in hemagglutination, serum resistance, adhesion to epithelial cells and virulence.
Mil-Homens D, Fialho AM
PLoS One 2012;7(7):e41747
PubMed ID: 22848588