Strain |
Burkholderia cenocepacia J2315
GCF_000009485.1|latest |
Locus Tag |
BCAL3121
|
NCBI Locus Tag | QU43_RS52335 |
Name |
wbiG
|
Replicon | chromosome 1 |
Genomic location | 3412044 - 3413021 (- strand) |
Comment | Belongs to the O antigen biosynthesis gene cluster |
RefSeq | YP_002232232.1 |
GI | 206561467 |
Entrez | 6934241 |
GI | 206561467 |
INSDC | CAR53445.1 |
NCBI Locus Tag | QU43_RS52335 |
NCBI Old Locus Tag | BCAL3121 |
RefSeq | YP_002232232.1 |
UniParc | UPI00017B998B |
UniProtKB Acc | B4ECE2 |
UniProtKB ID | B4ECE2_BURCJ |
UniRef100 | UniRef100_B4ECE2 |
UniRef50 | UniRef50_A9AF88 |
UniRef90 | UniRef90_B4ECE2 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
putative nucleotide sugar epimerase/dehydratase
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | 2.33 |
Kyte-Doolittle Hydrophobicity Value | -0.016 |
Molecular Weight (kDa) | 34977.6 |
Isoelectric Point (pI) | 7.99 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | BGD |
Category | Lipopolysaccharide O antigen |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Rattus norvegicus |
Notes | wbiG mutant attenuated for virulence in agar bead model of chronic lung infection |
Reference | 15213146 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 632 genera
|
Burkholderia Ortholog Group |
BG000740 (630 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BCAL3121
Search term: wbiG
Search term: putative nucleotide sugar epimerase/dehydratase
|
Reconstitution of O-specific lipopolysaccharide expression in Burkholderia cenocepacia strain J2315, which is associated with transmissible infections in patients with cystic fibrosis.
Ortega X, Hunt TA, Loutet S, Vinion-Dubiel AD, Datta A, Choudhury B, Goldberg JB, Carlson R, Valvano MA
J Bacteriol 2005 Feb;187(4):1324-33
PubMed ID: 15687196
|
Insect Gut Symbiont Susceptibility to Host Antimicrobial Peptides Caused by Alteration of the Bacterial Cell Envelope.
Kim JK, Son DW, Kim CH, Cho JH, Marchetti R, Silipo A, Sturiale L, Park HY, Huh YR, Nakayama H, Fukatsu T, Molinaro A, Lee BL
J Biol Chem 2015 Aug 21;290(34):21042-53
PubMed ID: 26116716
|