Burkholderia cenocepacia J2315, BCAL2947

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2947
NCBI Locus TagQU43_RS51380
Name
Replicon chromosome 1
Genomic location 3225696 - 3226868 (- strand)

Cross-References

RefSeq WP_006486912.1
GI 206561282
Entrez 6934217
GI 206561282
INSDC CAR53249.1
NCBI Locus Tag QU43_RS51380
NCBI Old Locus Tag BCAL2947
RefSeq WP_006486912.1,GeneID
UniParc UPI00017B9734
UniProtKB Acc B4EB37
UniProtKB ID B4EB37_BURCJ
UniRef100 UniRef100_B4EB37
UniRef50 UniRef50_A2RPS9
UniRef90 UniRef90_A0A071MH76

Product

Feature Type CDS
Coding Frame 1
Product Name
tetratricopeptide repeat protein
Synonyms
Evidence for Translation
Charge (pH 7) -4.76
Kyte-Doolittle Hydrophobicity Value -0.322
Molecular Weight (kDa) 43816.4
Isoelectric Point (pI) 6.19

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 140 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000892 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2947

Human Homologs

References

A complete lipopolysaccharide inner core oligosaccharide is required for resistance of Burkholderia cenocepacia to antimicrobial peptides and bacterial survival in vivo.
Loutet SA, Flannagan RS, Kooi C, Sokol PA, Valvano MA
J Bacteriol 2006 Mar;188(6):2073-80
PubMed ID: 16513737