Burkholderia cenocepacia J2315, BCAL2942 (cysM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2942
NCBI Locus TagQU43_RS51355
Name
cysM
Replicon chromosome 1
Genomic location 3220657 - 3221559 (- strand)

Cross-References

RefSeq WP_012492863.1
GI 206561277
Entrez 6932890
GI 206561277
INSDC CAR53243.1
NCBI Locus Tag QU43_RS51355
NCBI Old Locus Tag BCAL2942
RefSeq WP_012492863.1,GeneID
UniParc UPI00017B972F
UniProtKB Acc B4EB32
UniProtKB ID B4EB32_BURCJ
UniRef100 UniRef100_B4EB32
UniRef50 UniRef50_P16703
UniRef90 UniRef90_B4EB32

Product

Feature Type CDS
Coding Frame 1
Product Name
cysteine synthase B
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -2.57
Kyte-Doolittle Hydrophobicity Value -0.175
Molecular Weight (kDa) 32449.8
Isoelectric Point (pI) 5.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 625 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000897 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2942
Search term: cysM

Human Homologs

Ensembl 97, assembly GRCh38.p12
cystathionine-beta-synthase [Source:HGNC Symbol;Acc:HGNC:1550]
E-value: 1.2e-44
Percent Identity: 37.6
Ensembl 97, assembly GRCh38.p12
cystathionine-beta-synthase like [Source:HGNC Symbol;Acc:HGNC:51829]
E-value: 1.2e-44
Percent Identity: 37.6
Ensembl 97, assembly GRCh38.p12
cystathionine-beta-synthase like [Source:HGNC Symbol;Acc:HGNC:51829]
E-value: 1.2e-44
Percent Identity: 37.6
Ensembl 97, assembly GRCh38.p12
cystathionine-beta-synthase [Source:HGNC Symbol;Acc:HGNC:1550]
E-value: 1.2e-44
Percent Identity: 37.6
Ensembl 97, assembly GRCh38.p12
cystathionine-beta-synthase [Source:HGNC Symbol;Acc:HGNC:1550]
E-value: 1.2e-44
Percent Identity: 37.6
Ensembl 97, assembly GRCh38.p12
cystathionine-beta-synthase like [Source:HGNC Symbol;Acc:HGNC:51829]
E-value: 1.2e-44
Percent Identity: 37.6
Ensembl 97, assembly GRCh38.p12
cystathionine-beta-synthase like [Source:HGNC Symbol;Acc:HGNC:51829]
E-value: 1.2e-44
Percent Identity: 37.6
Ensembl 97, assembly GRCh38.p12
cystathionine-beta-synthase like [Source:HGNC Symbol;Acc:HGNC:51829]
E-value: 1.2e-44
Percent Identity: 37.6
Ensembl 97, assembly GRCh38.p12
cystathionine-beta-synthase [Source:HGNC Symbol;Acc:HGNC:1550]
E-value: 1.2e-44
Percent Identity: 37.6

References

A complete lipopolysaccharide inner core oligosaccharide is required for resistance of Burkholderia cenocepacia to antimicrobial peptides and bacterial survival in vivo.
Loutet SA, Flannagan RS, Kooi C, Sokol PA, Valvano MA
J Bacteriol 2006 Mar;188(6):2073-80
PubMed ID: 16513737