Burkholderia cenocepacia J2315, BCAL2830

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2830
NCBI Locus TagQU43_RS50765
Name
Replicon chromosome 1
Genomic location 3108127 - 3109473 (- strand)

Cross-References

RefSeq WP_012492850.1
GI 206561167
Entrez 6932827
GI 206561167
INSDC CAR53130.1
NCBI Locus Tag QU43_RS50765
NCBI Old Locus Tag BCAL2830
RefSeq WP_012492850.1,GeneID
UniParc UPI00017B9988
UniProtKB Acc B4EA14
UniProtKB ID B4EA14_BURCJ
UniRef100 UniRef100_B4EA14
UniRef50 UniRef50_Q13UK5
UniRef90 UniRef90_A4JHH0

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component regulatory system, sensor kinase protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -2.08
Kyte-Doolittle Hydrophobicity Value 0.067
Molecular Weight (kDa) 47927.2
Isoelectric Point (pI) 6.19

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 620 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002476 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2830

Human Homologs

References

Burkholderia cenocepacia requires a periplasmic HtrA protease for growth under thermal and osmotic stress and for survival in vivo.
Flannagan RS, Aubert D, Kooi C, Sokol PA, Valvano MA
Infect Immun 2007 Apr;75(4):1679-89
PubMed ID: 17220310