Burkholderia cenocepacia J2315, BCAL2405 (waaL)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL2405
NCBI Locus Tag	QU43_RS48690
Name	waaL
Replicon	chromosome 1
Genomic location	2660394 - 2661680 (- strand)

Cross-References

RefSeq	WP_012492743.1
GI	206560764
Entrez	6932477
GI	206560764
INSDC	CAR52706.1
NCBI Locus Tag	QU43_RS48690
NCBI Old Locus Tag	BCAL2405
RefSeq	WP_012492743.1,GeneID
UniParc	UPI00017B985B
UniProtKB Acc	B4E6D1
UniProtKB ID	B4E6D1_BURCJ
UniRef100	UniRef100_A0A0D1BF73
UniRef50	UniRef50_N0ABU7
UniRef90	UniRef90_A0A095DS99

Product

Feature Type	CDS
Coding Frame	1
Product Name	hypothetical protein Product Name Confidence: Class 1
Synonyms	waaL
Evidence for Translation
Charge (pH 7)	19.21
Kyte-Doolittle Hydrophobicity Value	0.521
Molecular Weight (kDa)	47380.6
Isoelectric Point (pI)	10.66

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 3 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG006141 (372 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL2405 Search term: waaL

Human Homologs

References

Biosynthesis and structure of the Burkholderia cenocepacia K56-2 lipopolysaccharide core oligosaccharide: truncation of the core oligosaccharide leads to increased binding and sensitivity to polymyxin B. Ortega X, Silipo A, Saldías MS, Bates CC, Molinaro A, Valvano MA J Biol Chem 2009 Aug 7;284(32):21738-51 PubMed ID: 19525227