Burkholderia cenocepacia J2315, BCAL2157 (suhB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
Locus Tag
BCAL2157
NCBI Locus TagQU43_RS47400
Name
suhB
Replicon chromosome 1
Genomic location 2382131 - 2382934 (+ strand)

Cross-References

RefSeq WP_006493635.1
GI 206560520
Entrez 6932290
GI 206560520
INSDC CAR52459.1
NCBI Locus Tag QU43_RS47400
NCBI Old Locus Tag BCAL2157
RefSeq WP_006493635.1,GeneID
UniParc UPI00017B9531
UniProtKB Acc B4ED80
UniProtKB ID B4ED80_BURCJ
UniRef100 UniRef100_B4ED80
UniRef50 UniRef50_Q3JQS8
UniRef90 UniRef90_B4ED80

Product

Feature Type CDS
Coding Frame 1
Product Name
SuhB
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) -5.38
Kyte-Doolittle Hydrophobicity Value -0.216
Molecular Weight (kDa) 29504.1
Isoelectric Point (pI) 5.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 565 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001977 (678 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2157
Search term: suhB
Search term: SuhB

Human Homologs

Ensembl 83, assembly GRCh38
inositol(myo)-1(or 4)-monophosphatase 2 [Source:HGNC Symbol;Acc:HGNC:6051]
E-value: 1.5e-34
Percent Identity: 36.5

References

The suhB gene of Burkholderia cenocepacia is required for protein secretion, biofilm formation, motility and polymyxin B resistance.
Rosales-Reyes R, Saldías MS, Aubert DF, El-Halfawy OM, Valvano MA.
Microbiology. 2012 Sep;158(Pt 9):2315-24.
PubMed ID: 22767545