Burkholderia cenocepacia J2315, BCAL0342 (tssC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
Locus Tag
BCAL0342
NCBI Locus TagQU43_RS38245
Name
tssC
Synonym: bcsK
Replicon chromosome 1
Genomic location 367436 - 368926 (+ strand)
CommentPart of the T6SS gene cluster

Cross-References

RefSeq WP_006484397.1
GI 206558748
Entrez 6930887
GI 206558748
INSDC CAR50652.1
NCBI Locus Tag QU43_RS38245
NCBI Old Locus Tag BCAL0342
RefSeq WP_006484397.1,GeneID
UniParc UPI00017B90FF
UniProtKB Acc B4E6R4
UniProtKB ID B4E6R4_BURCJ
UniRef100 UniRef100_A0A095DPV8
UniRef50 UniRef50_A0A0B6RY49
UniRef90 UniRef90_A0A0B6RY49

Product

Feature Type CDS
Coding Frame 1
Product Name
type VI secretion system protein TssC
Product Name Confidence: Class 1
Synonyms BcsK
Evidence for Translation
Charge (pH 7) -14.45
Kyte-Doolittle Hydrophobicity Value -0.278
Molecular Weight (kDa) 54822.0
Isoelectric Point (pI) 5.01

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 1
Outer Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 111 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000367 (656 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL0342
Search term: tssC

References

BcsKC is an essential protein for the type VI secretion system activity in Burkholderia cenocepacia that forms an outer membrane complex with BcsLB.
Aubert D, MacDonald DK, Valvano MA.
J Biol Chem. 2010 Nov 12;285(46):35988-98.
PubMed ID: 20729192
A novel sensor kinase-response regulator hybrid controls biofilm formation and type VI secretion system activity in Burkholderia cenocepacia.
Aubert DF, Flannagan RS, Valvano MA.
Infect Immun. 2008 May;76(5):1979-91.
PubMed ID: 18316384
PubMed ID: 26364149