Burkholderia pseudomallei 1710b, BURPS1710b_A0577 (bsaW)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia pseudomallei 1710b
GCF_000012785.1|latest
Locus Tag
BURPS1710b_A0577
NCBI Locus TagBURPS1710B_RS21360
Name
bsaW
Synonym: spaP
Replicon chromosome II
Genomic location 770123 - 770803 (- strand)

Cross-References

RefSeq WP_004188067.1
GI 76819720
Entrez 3694224
GI 76819720
INSDC ABA53667.1
NCBI Locus Tag BURPS1710B_RS21360
NCBI Old Locus Tag BURPS1710b_A0577
RefSeq WP_004188067.1
UniParc UPI000043BD23
UniProtKB Acc Q3JL17
UniProtKB ID Q3JL17_BURP1
UniRef100 UniRef100_A0A069BE09
UniRef50 UniRef50_P40700
UniRef90 UniRef90_Q2T716

Product

Feature Type CDS
Coding Frame 1
Product Name
BsaW
Product Name Confidence: Class 2
Synonyms surface presentation of antigens protein SpaP
Evidence for Translation
Charge (pH 7) -5.59
Kyte-Doolittle Hydrophobicity Value 0.667
Molecular Weight (kDa) 24769.0
Isoelectric Point (pI) 4.58

Subcellular localization

Individual Mappings
Localization Confidence PMID
Flagellar
Note: This is based on PSORTb V3.0 secondary localization prediction
Class 3
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 325 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019840 (324 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BURPS1710b_A0577
Search term: bsaW
Search term: BsaW

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592