Burkholderia pseudomallei 668, BURPS668_A2179 (bsaM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia pseudomallei 668
GCF_000015905.1|latest
Locus Tag
BURPS668_A2179
NCBI Locus TagBURPS668_RS25975
Name
bsaM
Replicon chromosome II
Genomic location 2115415 - 2116701 (+ strand)

Cross-References

RefSeq WP_011853463.1
GI 126445031
Entrez 4886890
GI 126445031
INSDC ABN88027.1
NCBI Locus Tag BURPS668_RS25975
NCBI Old Locus Tag BURPS668_A2179
RefSeq WP_011853463.1
UniParc UPI0000F28BB6
UniProtKB Acc A3NLF2
UniProtKB ID A3NLF2_BURP6
UniRef100 UniRef100_A3NLF2
UniRef50 UniRef50_A3MCF1
UniRef90 UniRef90_A3MCF1

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system protein PrgH/EprH
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -3.91
Kyte-Doolittle Hydrophobicity Value -0.218
Molecular Weight (kDa) 46275.7
Isoelectric Point (pI) 6.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 13 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019855 (320 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BURPS668_A2179
Search term: bsaM

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592