Burkholderia pseudomallei 668, BURPS668_A2174 (bsaP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia pseudomallei 668
GCF_000015905.1|latest
Locus Tag
BURPS668_A2174
NCBI Locus TagBURPS668_RS25960
Name
bsaP
Replicon chromosome II
Genomic location 2111278 - 2112399 (- strand)

Cross-References

RefSeq WP_009972095.1
GI 126444754
Entrez 4888346
GI 126444754
INSDC ABN87750.1
NCBI Locus Tag BURPS668_RS25960
NCBI Old Locus Tag BURPS668_A2174
RefSeq WP_009972095.1
UniParc UPI000055AC3D
UniProtKB Acc A3NLE7
UniProtKB ID A3NLE7_BURP6
UniRef100 UniRef100_A3NLE7
UniRef50 UniRef50_Q2T723
UniRef90 UniRef90_Q2T723

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion regulator YopN/LcrE/InvE/MxiC
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -3.34
Kyte-Doolittle Hydrophobicity Value -0.264
Molecular Weight (kDa) 40426.0
Isoelectric Point (pI) 5.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 16 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019849 (321 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BURPS668_A2174
Search term: bsaP

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592