Burkholderia pseudomallei 668, BURPS668_A2161 (bipC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia pseudomallei 668
GCF_000015905.1|latest
Locus Tag
BURPS668_A2161
NCBI Locus TagBURPS668_RS25895
Name
bipC
Replicon chromosome II
Genomic location 2097940 - 2099205 (- strand)

Cross-References

RefSeq YP_001063155.1
GI 126444789
Entrez 4886021
GI 126444789
INSDC ABN87785.1
NCBI Locus Tag BURPS668_RS25895
NCBI Old Locus Tag BURPS668_A2161
RefSeq YP_001063155.1
UniParc UPI0000F58382
UniProtKB Acc A3NLD4
UniProtKB ID BIPC_BURP6
UniRef100 UniRef100_A3NLD4
UniRef50 UniRef50_A3MCG9
UniRef90 UniRef90_A3MCG9

Product

Feature Type CDS
Coding Frame 1
Product Name
translation initiation factor 2
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 5.63
Kyte-Doolittle Hydrophobicity Value -0.592
Molecular Weight (kDa) 44627.6
Isoelectric Point (pI) 9.50

Subcellular localization

Individual Mappings
Localization Confidence PMID
Host Associated
Note: This is based on PSORTb V3.0 secondary localization prediction
Class 3
Unknown (This protein may have multiple localization sites) Class 3
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Pathogenic
Found only in pathogenic strains
Hits to this gene were found in 2 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019833 (317 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BURPS668_A2161
Search term: bipC

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592