Burkholderia pseudomallei 1106a, BURPS1106A_A2073 (bipC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia pseudomallei 1106a
GCF_000015925.1|latest
Locus Tag
BURPS1106A_A2073
NCBI Locus TagBURPS1106A_RS25770
Name
bipC
Replicon chromosome II
Genomic location 2036554 - 2037819 (- strand)

Cross-References

RefSeq YP_001076106.1
GI 126456098
Entrez 4905196
GI 126456098
INSDC ABN93279.1
NCBI Locus Tag BURPS1106A_RS25770
NCBI Old Locus Tag BURPS1106A_A2073
RefSeq YP_001076106.1
UniParc UPI0000E6A555
UniProtKB Acc A3P6Z6
UniProtKB ID BIPC_BURP0
UniRef100 UniRef100_A3P6Z6
UniRef50 UniRef50_A3MCG9
UniRef90 UniRef90_A3MCG9

Product

Feature Type CDS
Coding Frame 1
Product Name
IpaC/SipC family type III secretion target protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 6.63
Kyte-Doolittle Hydrophobicity Value -0.579
Molecular Weight (kDa) 44537.5
Isoelectric Point (pI) 9.78

Subcellular localization

Individual Mappings
Localization Confidence PMID
Host Associated
Note: This is based on PSORTb V3.0 secondary localization prediction
 Class 3
Unknown (This protein may have multiple localization sites) Class 3
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Pathogenic
Found only in pathogenic strains
Hits to this gene were found in 2 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019833 (317 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BURPS1106A_A2073
Search term: bipC

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592