Burkholderia multivorans ATCC 17616, Bmul_4917 (bceD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia multivorans ATCC 17616 - Assembly GCF_000018505.1
Locus Tag
Bmul_4917
NCBI Locus TagBMUL_RS24805
Name
bceD
Replicon chromosome 2
Genomic location 2041417 - 2041860 (- strand)
CommentMember of the bce-I gene cluster

Cross-References

RefSeq WP_006399391.1
GI 161521453
Entrez 5768814
GI 161521453
NCBI Locus Tag BMUL_RS24805
NCBI Old Locus Tag Bmul_4917
RefSeq WP_006399391.1
UniProtKB Acc A9ANS9
UniProtKB ID A9ANS9_BURM1

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphotyrosine phosphatase BceD
Product Name Confidence: Class 2
Synonyms protein tyrosine phosphatase
Evidence for Translation
Charge (pH 7) 4.34
Kyte-Doolittle Hydrophobicity Value -0.276
Molecular Weight (kDa) 16323.5
Isoelectric Point (pI) 8.92

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 298 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004849 (632 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bmul_4917
Search term: bceD

References

Functional analysis of Burkholderia cepacia genes bceD and bceF, encoding a phosphotyrosine phosphatase and a tyrosine autokinase, respectively: role in exopolysaccharide biosynthesis and biofilm formation.
Ferreira AS, Leitão JH, Sousa SA, Cosme AM, Sá-Correia I, Moreira LM.
Appl Environ Microbiol. 2007 Jan;73(2):524-34.
PubMed ID: 17114319
Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS(1), Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM.
Appl Environ Microbiol. 2010 Jan;76(2):441-50.
PubMed ID: 19948863
PubMed ID: 26590274
PubMed ID: 25486990