Burkholderia multivorans ATCC 17616, Bmul_2133 (hpnJ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia multivorans ATCC 17616 - Assembly GCF_000018505.1
GCF_000018505.1|latest
Locus Tag
Bmul_2133
NCBI Locus TagBMUL_RS10785
Name
hpnJ
Replicon chromosome 1
Genomic location 2346274 - 2347695 (- strand)
CommentBelongs to putative hopanoid biosynthesis gene cluster

Cross-References

RefSeq WP_012213766.1
GI 161525303
Entrez 5766491
GI 161525303
NCBI Locus Tag BMUL_RS10785
NCBI Old Locus Tag Bmul_2133
RefSeq WP_012213766.1
UniProtKB Acc A9AD31
UniProtKB ID A9AD31_BURM1

Product

Feature Type CDS
Coding Frame 1
Product Name
hopanoid biosynthesis associated radical SAM protein HpnJ
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 3.21
Kyte-Doolittle Hydrophobicity Value -0.327
Molecular Weight (kDa) 53967.6
Isoelectric Point (pI) 7.81

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 269 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001014 (651 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bmul_2133
Search term: hpnJ

Human Homologs

References

Identification of hopanoid biosynthesis genes involved in polymyxin resistance in Burkholderia multivorans.
Malott RJ, Steen-Kinnaird BR, Lee TD, Speert DP
Antimicrob Agents Chemother 2012 Jan;56(1):464-71
PubMed ID: 22006009