Burkholderia mallei ATCC 23344, BMAA0729 (tssM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia mallei ATCC 23344
GCF_000011705.1|latest
Locus Tag
BMAA0729
Name
tssM
Replicon chromosome 2
Genomic location 736735 - 738159 (- strand)
CommentAn alternate start site identified in PMID:19168747 was used to replace the original start site.

Cross-References

RefSeq YP_338385.1
GI 77358950
NCBI Locus Tag BMAA0729
RefSeq YP_338385.1,GeneID

Product

Feature Type CDS
Coding Frame 1
Product Name
deubiquitinase TssM
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 2.04
Kyte-Doolittle Hydrophobicity Value -0.172
Molecular Weight (kDa) 49395.8
Isoelectric Point (pI) 7.45

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019346 (317 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMAA0729
Search term: tssM

Human Homologs

References

Burkholderia mallei tssM encodes a putative deubiquitinase that is secreted and expressed inside infected RAW 264.7 murine macrophages.
Shanks J, Burtnick MN, Brett PJ, Waag DM, Spurgers KB, Ribot WJ, Schell MA, Panchal RG, Gherardini FC, Wilkinson KD, Deshazer D
Infect Immun 2009 Apr;77(4):1636-48
PubMed ID: 19168747