Burkholderia mallei NCTC 10229, BMA10229_2057 (bsaM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia mallei NCTC 10229
GCF_000015605.1|latest
Locus Tag
BMA10229_2057
NCBI Locus TagBMA10229_RS08910
Name
bsaM
Replicon chromosome II
Genomic location 2108485 - 2109771 (- strand)

Cross-References

RefSeq WP_004198991.1
GI 124382776
Entrez 4790224
GI 124382776
INSDC ABM98457.2
NCBI Locus Tag BMA10229_RS08910
NCBI Old Locus Tag BMA10229_2057
RefSeq WP_004198991.1
UniParc UPI0000441484
UniProtKB Acc A2S1N2
UniProtKB Acc A2S1N2
UniProtKB ID A2S1N2_BURM9
UniProtKB ID A2S1N4_BURM9
UniRef100 UniRef100_A3MCF1
UniRef50 UniRef50_A3MCF1
UniRef90 UniRef90_A3MCF1

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system protein BsaM
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -3.90
Kyte-Doolittle Hydrophobicity Value -0.207
Molecular Weight (kDa) 46321.8
Isoelectric Point (pI) 6.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search
Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 13 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019855 (320 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMA10229_2057
Search term: bsaM

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592