Burkholderia cenocepacia MC0-3, Bcenmc03_4197

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia MC0-3
GCF_000019505.1|latest
Locus Tag
Bcenmc03_4197
NCBI Locus TagBCENMC03_RS21160
Name
Replicon chromosome 2
Genomic location 1132491 - 1133195 (- strand)

Cross-References

RefSeq WP_012338856.1
GI 170736578
Entrez 6127030
GI 170736578
NCBI Locus Tag BCENMC03_RS21160
NCBI Old Locus Tag Bcenmc03_4197
RefSeq WP_012338856.1
UniProtKB Acc B1K7J5
UniProtKB ID B1K7J5_BURCC

Product

Feature Type CDS
Coding Frame 1
Product Name
VirB8 family protein
Synonyms
Evidence for Translation
Charge (pH 7) -2.07
Kyte-Doolittle Hydrophobicity Value -0.262
Molecular Weight (kDa) 26233.5
Isoelectric Point (pI) 6.14

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 55 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006329 (52 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcenmc03_4197

Human Homologs

References

Involvement of a plasmid-encoded type IV secretion system in the plant tissue watersoaking phenotype of Burkholderia cenocepacia.
Engledow AS, Medrano EG, Mahenthiralingam E, LiPuma JJ, Gonzalez CF
J Bacteriol 2004 Sep;186(18):6015-24
PubMed ID: 15342570
Two type IV secretion systems with different functions in Burkholderia cenocepacia K56-2.
Zhang R, LiPuma JJ, Gonzalez CF
Microbiology 2009 Dec;155(Pt 12):4005-4013
PubMed ID: 19744991
A type IV secretion system contributes to intracellular survival and replication of Burkholderia cenocepacia.
Sajjan SU, Carmody LA, Gonzalez CF, LiPuma JJ
Infect Immun 2008 Dec;76(12):5447-55
PubMed ID: 18824538