Burkholderia cenocepacia MC0-3, Bcenmc03_0301 (hppD)

Gene Feature Overview

Strain	Burkholderia cenocepacia MC0-3 GCF_000019505.1|latest
Locus Tag	Bcenmc03_0301
NCBI Locus Tag	BCENMC03_RS01535
Name	hppD
Replicon	chromosome 1
Genomic location	334724 - 335821 (- strand)

Cross-References

RefSeq	WP_006477405.1
GI	170731656
Entrez	6121984
GI	170731656
INSDC	ACA89481.1
NCBI Locus Tag	BCENMC03_RS01535
NCBI Old Locus Tag	Bcenmc03_0301
RefSeq	WP_006477405.1
UniParc	UPI000052EFB3
UniProtKB Acc	B1JTP1
UniProtKB ID	B1JTP1_BURCC
UniRef100	UniRef100_B1JTP1
UniRef50	UniRef50_Q5ZT84
UniRef90	UniRef90_Q2STZ8

Product

Feature Type	CDS
Coding Frame	1
Product Name	4-hydroxyphenylpyruvate dioxygenase Product Name Confidence: Class 1
Synonyms	4-hydroxyphenylpyruvic acid dioxygenase HppD
Evidence for Translation
Charge (pH 7)	-8.64
Kyte-Doolittle Hydrophobicity Value	-0.396
Molecular Weight (kDa)	41136.1
Isoelectric Point (pI)	5.45

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 221 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000231 (655 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: Bcenmc03_0301 Search term: hppD Search term: 4-hydroxyphenylpyruvate dioxygenase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000335060 4-hydroxyphenylpyruvate dioxygenase like [Source:HGNC Symbol;Acc:HGNC:28242] E-value: 7.6e-14 Percent Identity: 32.0

References