Burkholderia xenovorans LB400, Bxe_A0793 (fusA)

Gene Feature Overview

Strain	Burkholderia xenovorans LB400 (Paraburkholderia) GCF_000013645.1|latest
Locus Tag	Bxe_A0793
NCBI Locus Tag	BXE_RS17930
Name	fusA
Replicon	chromosome 1
Genomic location	4001300 - 4003405 (+ strand)

Cross-References

RefSeq	WP_011489642.1
GI	91784987
Entrez	4005598
GI	91784987
INSDC	ABE32141.1
NCBI Locus Tag	BXE_RS17930
NCBI Old Locus Tag	Bxe_A0793
RefSeq	WP_011489642.1,GeneID
UniParc	UPI000037E921
UniProtKB Acc	Q13UU8
UniProtKB ID	EFG1_BURXL
UniRef100	UniRef100_Q13UU8
UniRef50	UniRef50_Q9SI75
UniRef90	UniRef90_Q1BU86

Product

Feature Type	CDS
Coding Frame	1
Product Name	elongation factor G Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7)	-18.70
Kyte-Doolittle Hydrophobicity Value	-0.332
Molecular Weight (kDa)	77747.2
Isoelectric Point (pI)	5.25

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000255 (1306 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: Bxe_A0793 Search term: fusA Search term: elongation factor G

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000419038 G elongation factor mitochondrial 1 [Source:HGNC Symbol;Acc:HGNC:13780] E-value: 1.5e-151 Percent Identity: 43.7

References

Chlorobenzoate inhibits growth and induces stress proteins in the PCB-degrading bacterium Burkholderia xenovorans LB400. Martínez P, Agulló L, Hernández M, Seeger M Arch Microbiol 2007 Sep;188(3):289-97 PubMed ID: 17522847