Burkholderia vietnamiensis G4, Bcep1808_5783

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia vietnamiensis G4
GCF_000016205.1|latest
Locus Tag
Bcep1808_5783
NCBI Locus TagBCEP1808_RS28725
Name
Replicon chromosome 3
Genomic location 365132 - 365473 (+ strand)

Cross-References

RefSeq WP_011879922.1
GI 134291201
Entrez 4948687
GI 134291201
NCBI Locus Tag BCEP1808_RS28725
NCBI Old Locus Tag Bcep1808_5783
RefSeq WP_011879922.1
UniProtKB Acc A4JR12
UniProtKB ID A4JR12_BURVG

Product

Feature Type CDS
Coding Frame 1
Product Name
type IV secretion system protein VirB2/TraC
Synonyms
Evidence for Translation
Charge (pH 7) 8.40
Kyte-Doolittle Hydrophobicity Value 0.604
Molecular Weight (kDa) 12326.6
Isoelectric Point (pI) 11.49

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 9 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006325 (52 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcep1808_5783

Human Homologs

References

Involvement of a plasmid-encoded type IV secretion system in the plant tissue watersoaking phenotype of Burkholderia cenocepacia.
Engledow AS, Medrano EG, Mahenthiralingam E, LiPuma JJ, Gonzalez CF
J Bacteriol 2004 Sep;186(18):6015-24
PubMed ID: 15342570
Two type IV secretion systems with different functions in Burkholderia cenocepacia K56-2.
Zhang R, LiPuma JJ, Gonzalez CF
Microbiology 2009 Dec;155(Pt 12):4005-4013
PubMed ID: 19744991
A type IV secretion system contributes to intracellular survival and replication of Burkholderia cenocepacia.
Sajjan SU, Carmody LA, Gonzalez CF, LiPuma JJ
Infect Immun 2008 Dec;76(12):5447-55
PubMed ID: 18824538