Burkholderia thailandensis E264 ATCC 700388, BTH_I0209 (rqpR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia thailandensis E264 ATCC 700388
GCF_000012365.1|latest
Locus Tag
BTH_I0209
NCBI Locus TagBTH_RS13265
Name
rqpR
Replicon chromosome I
Genomic location 243053 - 243709 (- strand)
Transposon Mutants 3 transposon mutants in E264 ATCC 700388

Cross-References

RefSeq YP_440767.1
GI 83721309
Entrez 3849445
GI 83721309
INSDC AIP26021.1
NCBI Locus Tag BTH_RS13265
NCBI Old Locus Tag BTH_I0209
RefSeq WP_009893489.1
UniParc UPI0000668622
UniProtKB Acc Q2T232
UniProtKB ID Q2T232_BURTA
UniRef100 UniRef100_Q2T232
UniRef50 UniRef50_A0A060P7Z6
UniRef90 UniRef90_Q2T232

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component regulatory system, response regulator RqpR
Product Name Confidence: Class 2
Synonyms LuxR family DNA-binding response regulator
Evidence for Translation
Charge (pH 7) 1.66
Kyte-Doolittle Hydrophobicity Value 0.080
Molecular Weight (kDa) 24140.9
Isoelectric Point (pI) 8.20

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 622 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002880 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BTH_I0209
Search term: rqpR

Human Homologs

References

A novel two-component system modulates quorum sensing and pathogenicity in Burkholderia cenocepacia.
Cui C, Yang C, Song S, Fu S, Sun X, Yang L, He F, Zhang LH, Zhang Y, Deng Y
Mol Microbiol 2018 Apr;108(1):32-44
PubMed ID: 29363827