Strain |
Burkholderia thailandensis E264 ATCC 700388
GCF_000012365.1|latest |
Locus Tag |
BTH_II2099
|
NCBI Locus Tag | BTH_RS10740 |
Name |
malM
|
Replicon | chromosome II |
Genomic location | 2577785 - 2579653 (+ strand) |
Transposon Mutants | 2 transposon mutants in E264 ATCC 700388 |
Comment | Belongs to the malleilactone biosynthetic gene cluster |
RefSeq | YP_440287.1 |
GI | 83718033 |
Entrez | 3844687 |
GI | 83718033 |
NCBI Locus Tag | BTH_RS10740 |
NCBI Old Locus Tag | BTH_II2099 |
RefSeq | WP_009894059.1 |
UniProtKB Acc | Q2T3G2 |
UniProtKB ID | Q2T3G2_BURTA |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
MalM
|
Synonyms |
AMP-binding domain-containing protein |
Evidence for Translation | |
Charge (pH 7) | -5.85 |
Kyte-Doolittle Hydrophobicity Value | -0.067 |
Molecular Weight (kDa) | 66879.0 |
Isoelectric Point (pI) | 6.35 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 539 genera
|
Burkholderia Ortholog Group |
BG019792 (370 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BTH_II2099
Search term: malM
Search term: MalM
|
Ensembl
97, assembly
GRCh38.p12
|
acyl-CoA synthetase bubblegum family member 1 [Source:HGNC Symbol;Acc:HGNC:29567]
E-value:
2.1e-11
Percent Identity:
25.4
|
Ensembl
97, assembly
GRCh38.p12
|
acyl-CoA synthetase bubblegum family member 1 [Source:HGNC Symbol;Acc:HGNC:29567]
E-value:
2.1e-11
Percent Identity:
25.4
|
Global Awakening of Cryptic Biosynthetic Gene Clusters in Burkholderia thailandensis.
Gupta A, Bedre R, Thapa SS, Sabrin A, Wang G, Dassanayake M, Grove A
ACS Chem Biol 2017 Dec 15;12(12):3012-3021
PubMed ID: 29087175
|
Malleilactone, a polyketide synthase-derived virulence factor encoded by the cryptic secondary metabolome of Burkholderia pseudomallei group pathogens.
Biggins JB, Ternei MA, Brady SF
J Am Chem Soc 2012 Aug 15;134(32):13192-5
PubMed ID: 22765305
|