Burkholderia thailandensis E264 ATCC 700388, BTH_II0821 (orgB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia thailandensis E264 ATCC 700388
GCF_000012365.1|latest
Locus Tag
BTH_II0821
NCBI Locus TagBTH_RS04270
Name
orgB
Replicon chromosome II
Genomic location 962902 - 963687 (- strand)

Cross-References

RefSeq YP_439018.1
GI 83717498
Entrez 3846345
GI 83717498
NCBI Locus Tag BTH_RS04270
NCBI Old Locus Tag BTH_II0821
RefSeq WP_009896102.1
UniProtKB Acc Q2T731
UniProtKB ID Q2T731_BURTA

Product

Feature Type CDS
Coding Frame 1
Product Name
Oxygen-regulated invasion protein OrgB
Product Name Confidence: Class 2
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) -1.94
Kyte-Doolittle Hydrophobicity Value -0.375
Molecular Weight (kDa) 28362.3
Isoelectric Point (pI) 6.37

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 5 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG017454 (359 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BTH_II0821
Search term: orgB

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592