Burkholderia thailandensis E264; ATCC 700388, BTH_II0545 (bceD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia thailandensis E264; ATCC 700388
Locus Tag
BTH_II0545
NCBI Locus TagBTH_RS02845
Name
bceD
Replicon chromosome II
Genomic location 647959 - 648393 (+ strand)
Transposon Mutants 1 transposon mutants in E264; ATCC 700388
CommentMember of the bce-I gene cluster

Cross-References

RefSeq YP_438745.1
GI 83717591
Entrez 3846418
GI 83717591
INSDC AIP27737.1
NCBI Locus Tag BTH_RS02845
NCBI Old Locus Tag BTH_II0545
RefSeq WP_009895608.1
UniParc UPI0000667848
UniProtKB Acc Q2T7V4
UniProtKB ID Q2T7V4_BURTA
UniRef100 UniRef100_Q2T7V4
UniRef50 UniRef50_Q2T7V4
UniRef90 UniRef90_Q2T7V4

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphotyrosine phosphatase BceD
Product Name Confidence: Class 2
Synonyms low molecular weight protein-tyrosine-phosphatase wzb
Evidence for Translation
Charge (pH 7) 0.62
Kyte-Doolittle Hydrophobicity Value -0.239
Molecular Weight (kDa) 16105.2
Isoelectric Point (pI) 7.44

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 341 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004849 (632 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BTH_II0545
Search term: bceD

References

Functional analysis of Burkholderia cepacia genes bceD and bceF, encoding a phosphotyrosine phosphatase and a tyrosine autokinase, respectively: role in exopolysaccharide biosynthesis and biofilm formation.
Ferreira AS, Leitão JH, Sousa SA, Cosme AM, Sá-Correia I, Moreira LM.
Appl Environ Microbiol. 2007 Jan;73(2):524-34.
PubMed ID: 17114319
Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS(1), Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM.
Appl Environ Microbiol. 2010 Jan;76(2):441-50.
PubMed ID: 19948863
PubMed ID: 26590274
PubMed ID: 25486990