Burkholderia pseudomallei K96243, BPSS2105 (TssL-6)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS2105
Name
TssL-6
Replicon chromosome 2
Genomic location 2851212 - 2852528 (- strand)

Cross-References

RefSeq YP_112104.1
GI 53723119
Entrez 3095757
GI 53723119
INSDC CAH39585.1
NCBI Locus Tag BPSS2105
RefSeq YP_112104.1,GeneID
UniParc UPI000043BF4F
UniProtKB Acc Q63IG8
UniProtKB ID Q63IG8_BURPS
UniRef100 UniRef100_A0A069BI25
UniRef50 UniRef50_D0FP53
UniRef90 UniRef90_Q3JJ90

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 7.01
Kyte-Doolittle Hydrophobicity Value -0.120
Molecular Weight (kDa) 47346.2
Isoelectric Point (pI) 8.95

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 383 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG016595 (520 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS2105
Search term: TssL-6

Human Homologs

References

In vivo expression technology identifies a type VI secretion system locus in Burkholderia pseudomallei that is induced upon invasion of macrophages.
Shalom G, Shaw JG, Thomas MS
Microbiology 2007 Aug;153(Pt 8):2689-2699
PubMed ID: 17660433