Burkholderia pseudomallei K96243, BPSS2094 (TssH-6)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS2094
Name
TssH-6
Replicon chromosome 2
Genomic location 2833428 - 2836094 (- strand)

Cross-References

RefSeq YP_112093.1
GI 53723108
Entrez 3095599
GI 53723108
INSDC CAH39574.1
NCBI Locus Tag BPSS2094
RefSeq YP_112093.1,GeneID
UniParc UPI000043BF44
UniProtKB Acc Q63IH9
UniProtKB ID Q63IH9_BURPS
UniRef100 UniRef100_A0A069BBH6
UniRef50 UniRef50_Q9I742
UniRef90 UniRef90_Q2T8N3

Product

Feature Type CDS
Coding Frame 1
Product Name
Clp protease ATPase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724).
Charge (pH 7) -15.80
Kyte-Doolittle Hydrophobicity Value -0.017
Molecular Weight (kDa) 96413.0
Isoelectric Point (pI) 5.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 597 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG016581 (507 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS2094
Search term: TssH-6

Human Homologs

References

In vivo expression technology identifies a type VI secretion system locus in Burkholderia pseudomallei that is induced upon invasion of macrophages.
Shalom G, Shaw JG, Thomas MS
Microbiology 2007 Aug;153(Pt 8):2689-2699
PubMed ID: 17660433