Burkholderia pseudomallei K96243, BPSS1992

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSS1992
Name
Replicon	chromosome 2
Genomic location	2693248 - 2695182 (- strand)

Cross-References

RefSeq	YP_111998.1
GI	53723013
Entrez	3096963
GI	53723013
INSDC	CAH39470.1
NCBI Locus Tag	BPSS1992
RefSeq	YP_111998.1,GeneID
UniParc	UPI000043BEE7
UniProtKB Acc	Q63IS4
UniProtKB ID	Q63IS4_BURPS
UniRef100	UniRef100_A0A069BI72
UniRef50	UniRef50_B4EHZ5
UniRef90	UniRef90_Q3JJJ5

Product

Feature Type	CDS
Coding Frame	1
Product Name	x-prolyl-dipeptidyl aminopeptidase
Synonyms
Evidence for Translation
Charge (pH 7)	-2.19
Kyte-Doolittle Hydrophobicity Value	-0.176
Molecular Weight (kDa)	68190.9
Isoelectric Point (pI)	6.66

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown (This protein may have multiple localization sites) Class 3 20472543 Extracellular Class 1 quantitative mass spectrometry evidence 25635268
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 68 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG004051 (593 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSS1992 Search term: x-prolyl-dipeptidyl aminopeptidase

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants. Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM Mol Cell Proteomics 2015 Apr;14(4):905-16 PubMed ID: 25635268