Burkholderia pseudomallei K96243, BPSS1734

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1734
Name
Replicon chromosome 2
Genomic location 2381113 - 2382861 (+ strand)

Cross-References

RefSeq YP_111740.1
GI 53722755
Entrez 3095121
GI 53722755
INSDC CAH39209.1
NCBI Locus Tag BPSS1734
RefSeq YP_111740.1,GeneID
UniParc UPI000043BDE5
UniProtKB Acc Q63JI2
UniProtKB ID Q63JI2_BURPS
UniRef100 UniRef100_Q63JI2
UniRef50 UniRef50_Q2T7K4
UniRef90 UniRef90_Q2T7K4

Product

Feature Type CDS
Coding Frame 1
Product Name
sedolisin
Synonyms
Evidence for Translation
Charge (pH 7) -6.24
Kyte-Doolittle Hydrophobicity Value -0.134
Molecular Weight (kDa) 61041.1
Isoelectric Point (pI) 6.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 57 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003033 (1733 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1734
Search term: sedolisin

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268