Burkholderia pseudomallei K96243, BPSS1684 (bceR)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSS1684
Name	bceR
Replicon	chromosome 2
Genomic location	2314235 - 2316697 (- strand)
Comment	Note that another gene (BCAM1493) for a two-component response regulator in B. cenocepacia J2315 was also assigned the name bceR at a later date (PMID:25519693).
Comment	Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis.
Comment	Member of the bce-II gene cluster

Cross-References

RefSeq	YP_111689.1
GI	53722704
Entrez	3096455
GI	53722704
INSDC	CAH39157.1
NCBI Locus Tag	BPSS1684
RefSeq	YP_111689.1,GeneID
UniParc	UPI000043BDB2
UniProtKB Acc	Q63JN3
UniProtKB ID	Q63JN3_BURPS
UniRef100	UniRef100_Q3JKJ2
UniRef50	UniRef50_A3P7L1
UniRef90	UniRef90_A3P7L1

Product

Feature Type	CDS
Coding Frame	1
Product Name	lipopolysaccharide biosynthesys-related glycosyltransferase Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7)	17.12
Kyte-Doolittle Hydrophobicity Value	0.027
Molecular Weight (kDa)	89860.3
Isoelectric Point (pI)	9.50

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 548 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003106 (652 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSS1684 Search term: bceR Search term: lipopolysaccharide biosynthesys-related glycosyltransferase

Human Homologs

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions. Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM Appl Environ Microbiol 2010 Jan;76(2):441-50 PubMed ID: 19948863