Burkholderia pseudomallei K96243, BPSS1588

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSS1588
Name
Replicon	chromosome 2
Genomic location	2160486 - 2161886 (+ strand)

Cross-References

RefSeq	YP_111596.1
GI	53722611
Entrez	3097129
GI	53722611
INSDC	CAH39063.1
NCBI Locus Tag	BPSS1588
RefSeq	YP_111596.1,GeneID
UniParc	UPI000043BD57
UniProtKB Acc	Q63JX6
UniProtKB ID	Q63JX6_BURPS
UniRef100	UniRef100_Q62AU8
UniRef50	UniRef50_Q2T769
UniRef90	UniRef90_Q2T769

Product

Feature Type	CDS
Coding Frame	1
Product Name	hypothetical protein
Synonyms
Evidence for Translation	Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (49.5 kDa, pI 6.04, PMID:21960737)
Charge (pH 7)	-1.45
Kyte-Doolittle Hydrophobicity Value	-0.111
Molecular Weight (kDa)	49278.9
Isoelectric Point (pI)	6.63

Subcellular localization

Individual Mappings	Localization Confidence PMID Outer Membrane Class 3 20472543 Extracellular Class 1 quantitative mass spectrometry evidence 25635268
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 2 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG019900 (323 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSS1588

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants. Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM Mol Cell Proteomics 2015 Apr;14(4):905-16 PubMed ID: 25635268