Strain |
Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest |
Locus Tag |
BPSS1516
|
Name |
bopC
|
Replicon | chromosome 2 |
Genomic location | 2068764 - 2070173 (- strand) |
Comment | This gene is part of the type III secretion system T3SS-3 (bsa) gene locus. bopC is also necessary for T6SS-1 function in macrophages (PMID: 21670170). |
RefSeq | YP_111522.1 |
GI | 53722537 |
Entrez | 3096078 |
GI | 53722537 |
NCBI Locus Tag | BPSS1516 |
RefSeq | YP_111522.1,GeneID |
UniProtKB Acc | Q63K50 |
UniProtKB ID | Q63K50_BURPS |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
type III secretion system effector BopC (T3SS-3)
|
Synonyms |
BopC |
Evidence for Translation | |
Charge (pH 7) | -2.01 |
Kyte-Doolittle Hydrophobicity Value | -0.361 |
Molecular Weight (kDa) | 51537.1 |
Isoelectric Point (pI) | 6.76 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | VFDB : VF0428 |
Category | T3SS-3 |
Evidence |
ECO:0000314
direct assay evidence used in manual assertion
|
Host Organism | |
Notes | |
Reference | 17984080 |
Results |
Pathogenic
Found only in pathogenic strains
Hits to this gene were found in 3 genera
|
Burkholderia Ortholog Group |
BG020942 (270 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BPSS1516
Search term: bopC
Search term: type III secretion system effector BopC (T3SS-3)
|
BopC is a type III secreted effector protein of Burkholderia pseudomallei.
Muangman S, Korbsrisate S, Muangsombut V, Srinon V, Adler NL, Schroeder GN, Frankel G, Galyov EE
FEMS Microbiol Lett 2011 Oct;323(1):75-82
PubMed ID: 22092682
|
Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592
|
Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268
|
Regulation of type VI secretion system during Burkholderia pseudomallei infection.
Chen Y, Wong J, Sun GW, Liu Y, Tan GY, Gan YH
Infect Immun 2011 Aug;79(8):3064-73
PubMed ID: 21670170
|
Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152
|