Burkholderia pseudomallei K96243, BPSS1249

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1249
Name
Replicon chromosome 2
Genomic location 1691427 - 1693619 (+ strand)

Cross-References

RefSeq YP_111257.1
GI 53722272
Entrez 3095693
GI 53722272
INSDC CAH38716.1
NCBI Locus Tag BPSS1249
RefSeq YP_111257.1,GeneID
UniParc UPI000043BC11
UniProtKB Acc Q63KW4
UniProtKB ID Q63KW4_BURPS
UniRef100 UniRef100_Q3JLZ5
UniRef50 UniRef50_Q2T637
UniRef90 UniRef90_A3P5V1

Product

Feature Type CDS
Coding Frame 1
Product Name
lipoprotein
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724).
Charge (pH 7) -7.33
Kyte-Doolittle Hydrophobicity Value -0.100
Molecular Weight (kDa) 78622.0
Isoelectric Point (pI) 5.39

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Periplasmic Class 3
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 4 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001766 (583 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1249
Search term: lipoprotein

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268