Burkholderia pseudomallei K96243, BPSS0974

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS0974
Name
Replicon chromosome 2
Genomic location 1289873 - 1291492 (- strand)

Cross-References

RefSeq YP_110982.1
GI 53721997
Entrez 3097149
GI 53721997
INSDC CAH38436.1
NCBI Locus Tag BPSS0974
RefSeq YP_110982.1,GeneID
UniParc UPI000043BB06
UniProtKB Acc Q63LN9
UniProtKB ID Q63LN9_BURPS
UniRef100 UniRef100_A0A095QUT6
UniRef50 UniRef50_A9AR40
UniRef90 UniRef90_A1UV29

Product

Feature Type CDS
Coding Frame 1
Product Name
peptidase
Synonyms
Evidence for Translation
Charge (pH 7) -6.78
Kyte-Doolittle Hydrophobicity Value -0.029
Molecular Weight (kDa) 53865.2
Isoelectric Point (pI) 5.12

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Extracellular Class 3
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 370 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003613 (639 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS0974
Search term: peptidase

Human Homologs

Ensembl 97, assembly GRCh38.p12
proprotein convertase subtilisin/kexin type 6 [Source:HGNC Symbol;Acc:HGNC:8569]
E-value: 1.2e-10
Percent Identity: 27.2
Ensembl 97, assembly GRCh38.p12
proprotein convertase subtilisin/kexin type 6 [Source:HGNC Symbol;Acc:HGNC:8569]
E-value: 1.2e-10
Percent Identity: 27.2
Ensembl 97, assembly GRCh38.p12
proprotein convertase subtilisin/kexin type 6 [Source:HGNC Symbol;Acc:HGNC:8569]
E-value: 1.2e-10
Percent Identity: 27.2
Ensembl 97, assembly GRCh38.p12
proprotein convertase subtilisin/kexin type 6 [Source:HGNC Symbol;Acc:HGNC:8569]
E-value: 1.2e-10
Percent Identity: 27.2
Ensembl 97, assembly GRCh38.p12
proprotein convertase subtilisin/kexin type 6 [Source:HGNC Symbol;Acc:HGNC:8569]
E-value: 1.2e-10
Percent Identity: 27.2
Ensembl 97, assembly GRCh38.p12
proprotein convertase subtilisin/kexin type 6 [Source:HGNC Symbol;Acc:HGNC:8569]
E-value: 1.2e-10
Percent Identity: 27.2
Ensembl 97, assembly GRCh38.p12
proprotein convertase subtilisin/kexin type 6 [Source:HGNC Symbol;Acc:HGNC:8569]
E-value: 1.2e-10
Percent Identity: 27.2

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268