Burkholderia pseudomallei K96243, BPSS0796 (boaA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS0796
Name
boaA
Replicon chromosome 2
Genomic location 1063333 - 1068294 (+ strand)

Cross-References

RefSeq YP_110805.1
GI 53721820
Entrez 3097081
GI 53721820
NCBI Locus Tag BPSS0796
RefSeq YP_110805.1,GeneID
UniProtKB Acc Q63M66
UniProtKB ID Q63M66_BURPS

Product

Feature Type CDS
Coding Frame 1
Product Name
Burkholderia oligomeric coiled-coil adhesin A, BoaA
Product Name Confidence: Class 1
Synonyms surface-exposed protein
Evidence for Translation
Charge (pH 7) -15.63
Kyte-Doolittle Hydrophobicity Value 0.243
Molecular Weight (kDa) 151574.1
Isoelectric Point (pI) 4.32

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database BGD
Category Trimeric autotransporter
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Mus musculus
Notes boaA mutation attenuated for virulence in BALB/c mouse model of melioidosis.
Reference 25830295
Source 2
Database VFDB : VF0434
Category Burkholderia oligomeric coiled-coil adhesin A
Evidence ECO:0000314
direct assay evidence used in manual assertion
Host Organism
Notes
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 74 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002926 (1913 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS0796
Search term: boaA

Human Homologs

References

Identification of Burkholderia mallei and Burkholderia pseudomallei adhesins for human respiratory epithelial cells.
Balder R, Lipski S, Lazarus JJ, Grose W, Wooten RM, Hogan RJ, Woods DE, Lafontaine ER
BMC Microbiol 2010 Sep 28;10:250
PubMed ID: 20920184