Burkholderia pseudomallei K96243, BPSS0618

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
Locus Tag
BPSS0618
Name
Replicon chromosome 2
Genomic location 843109 - 844812 (+ strand)

Cross-References

RefSeq YP_110639.1
GI 53721654
Entrez 3096614
GI 53721654
INSDC CAH38075.1
NCBI Locus Tag BPSS0618
RefSeq YP_110639.1,GeneID
UniParc UPI000043B9B3
UniProtKB Acc Q63MN2
UniProtKB ID Q63MN2_BURPS
UniRef100 UniRef100_Q63MN2
UniRef50 UniRef50_Q5P7E7
UniRef90 UniRef90_I6ADD2

Product

Feature Type CDS
Coding Frame 1
Product Name
AMP-binding protein
Synonyms
Evidence for Translation
Charge (pH 7) -3.66
Kyte-Doolittle Hydrophobicity Value -0.299
Molecular Weight (kDa) 63494.5
Isoelectric Point (pI) 6.38

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Extracellular Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 597 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003929 (637 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS0618

Human Homologs

Ensembl 86, assembly GRCh38.p7
acyl-CoA synthetase medium-chain family member 3 [Source:HGNC Symbol;Acc:HGNC:10522]
E-value: 5.6e-103
Percent Identity: 38.4

References

Quantitative Proteomic Analysis of Burkholderia pseudomallei Bsa Type III Secretion System Effectors Using Hypersecreting Mutants.
Vander Broek CW(1), Chalmers KJ(2), Stevens MP(1), Stevens JM(3).
Mol Cell Proteomics. 2015 Apr;14(4):905-16.
PubMed ID: 25635268