Burkholderia pseudomallei K96243, BPSS0548

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS0548
Name
Replicon chromosome 2
Genomic location 749113 - 750084 (+ strand)

Cross-References

RefSeq YP_110569.1
GI 53721584
Entrez 3095707
GI 53721584
INSDC CAH38005.1
NCBI Locus Tag BPSS0548
RefSeq YP_110569.1,GeneID
UniParc UPI000043B96E
UniProtKB Acc Q63MV0
UniProtKB ID Q63MV0_BURPS
UniRef100 UniRef100_A0A069B784
UniRef50 UniRef50_I1EZS2
UniRef90 UniRef90_A0B2E1

Product

Feature Type CDS
Coding Frame 1
Product Name
family M19 non-peptidase
Synonyms
Evidence for Translation
Charge (pH 7) -3.70
Kyte-Doolittle Hydrophobicity Value -0.191
Molecular Weight (kDa) 35828.5
Isoelectric Point (pI) 5.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 278 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004019 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS0548

Human Homologs

Ensembl 97, assembly GRCh38.p12
dipeptidase 2 [Source:HGNC Symbol;Acc:HGNC:23028]
E-value: 1.8e-22
Percent Identity: 25.2
Ensembl 97, assembly GRCh38.p12
dipeptidase 2 [Source:HGNC Symbol;Acc:HGNC:23028]
E-value: 1.8e-22
Percent Identity: 25.2

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268