Burkholderia pseudomallei K96243, BPSS0372

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS0372
Name
Replicon chromosome 2
Genomic location 510761 - 512296 (- strand)

Cross-References

RefSeq YP_110392.1
GI 53721407
Entrez 3096299
GI 53721407
INSDC CAH37820.1
NCBI Locus Tag BPSS0372
RefSeq YP_110392.1,GeneID
UniParc UPI000043B8C1
UniProtKB Acc Q63NC7
UniProtKB ID Q63NC7_BURPS
UniRef100 UniRef100_A0A095QLW3
UniRef50 UniRef50_D8NI54
UniRef90 UniRef90_Q141Z6

Product

Feature Type CDS
Coding Frame 1
Product Name
fumarate hydratase
Synonyms
Evidence for Translation
Charge (pH 7) -2.70
Kyte-Doolittle Hydrophobicity Value -0.088
Molecular Weight (kDa) 54774.8
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 378 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002085 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS0372

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268