Burkholderia pseudomallei K96243, BPSS0371 (bfr)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS0371
Name
bfr
Replicon chromosome 2
Genomic location 510130 - 510606 (- strand)

Cross-References

RefSeq YP_110391.1
GI 53721406
Entrez 3097235
GI 53721406
INSDC CAH37819.1
NCBI Locus Tag BPSS0371
RefSeq YP_110391.1,GeneID
UniParc UPI000043B8C0
UniProtKB Acc Q63NC8
UniProtKB ID Q63NC8_BURPS
UniRef100 UniRef100_A3MG45
UniRef50 UniRef50_D4ZKC2
UniRef90 UniRef90_A3MG45

Product

Feature Type CDS
Coding Frame 1
Product Name
bacterioferritin
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724). Found in at least two preparations.
Charge (pH 7) -12.65
Kyte-Doolittle Hydrophobicity Value -0.508
Molecular Weight (kDa) 18506.0
Isoelectric Point (pI) 4.50

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 232 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002086 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS0371
Search term: bfr
Search term: bacterioferritin

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268